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ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 7

LC-MS/MS vs HPLC for peptide analysis — November 2025

Dr.SportsMedIN Mon, Jul 22, 2024 at 3:37 PM 51 replies 2,260 viewsPage 7 of 11
MikeFit_NJ
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Oct 16, 2024 at 2:09 PM#31
Dr.SportsMedIN said:
Reporting back with a partial result, because a partial result is still better than silence.

This matches mine closely enough to be worth saying so out loud. The detail I would add is minor and it is already implied above.

Last edited: Oct 16, 2024 at 5:09 PM
23 21LeilaHI, marcus_mpls, DeniseRN_TPA and 20 others
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SteveThurs
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Oct 23, 2024 at 8:06 AM#32
Dr.SportsMedIN said:
Reporting back with a partial result, because a partial result is still better than silence.

There is a second half to this that has not been said yet. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Last edited: Oct 23, 2024 at 12:06 PM
24 22PurityPaulOR, MaxMetOK, MounjBrad and 21 others
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raj_cambridge
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Oct 30, 2024 at 1:59 AM#33

The figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

That is the short version; the long version is somebody else's post.

25 23TomTeleRx, DoseLogDan, SleepFixSam and 22 others
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Dr.EM_Chicago
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Nov 5, 2024 at 7:48 PM#34

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

26 24lucas_SP_BR, lisa_labSD, adam_van and 23 others
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HPLC_Greg
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Nov 12, 2024 at 1:34 PM#35
raj_cambridge said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

27 0SaraMom3, Dr.MetabolicMD, RetaRick_CA and 24 others
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