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ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 6

LC-MS/MS vs HPLC for peptide analysis — November 2025

Dr.SportsMedIN Mon, Jul 22, 2024 at 3:37 PM 51 replies 2,260 viewsPage 6 of 11
adam_van
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890
Nov 2024
Vancouver, CA
Sep 12, 2024 at 1:53 PM#26

A narrower follow-up, since the general answer is now clear:

How long did you give it before you decided it was working?

47 20FranDenver, Dr.BariatricHTX, LindaRN_retired and 44 others
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james_edin
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289
1,234
Sep 2024
Edinburgh, UK
Sep 19, 2024 at 9:32 AM#27
hank_denver said:
Practical: whatever you change, write down the date and the reason.

Pushing back on hank_denver here. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

48 21Dr.PathRoch, mona_PHX, andrew_nyc and 45 others
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BrianDallas92
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312
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Oct 2024
Dallas, TX
Sep 26, 2024 at 5:08 AM#28
hank_denver said:
Practical: whatever you change, write down the date and the reason.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

Last edited: Sep 26, 2024 at 6:08 AM
49 22andrew_nyc, Dr.EndoEP, GraceAZ_72 and 46 others
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bri_stats
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3,456
May 2024
Seattle, WA
Oct 3, 2024 at 12:40 AM#29
hank_denver said:
Practical: whatever you change, write down the date and the reason.

Bookmarking. The distinction being drawn above is the one nobody else makes.

50 23JessicaM_2024, TomFromTexas, mike.trainer_LA and 47 others
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Dr.SportsMedIN
Senior Member
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Feb 2024
Indianapolis, IN
Oct 9, 2024 at 8:08 PM#30

Reporting back.

Reporting back with a partial result, because a partial result is still better than silence. Two of the three things suggested helped; I cannot separate them and I am not going to pretend otherwise.

22 20rachel_ABQ, traveltech_sara, AttorneyGrant and 19 others
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