🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingPaid for independent testing and results did not match vendor COA — looking for input Page 4

Paid for independent testing and results did not match vendor COA — looking for input

PurityPaulOR Wed, Jan 24, 2024 at 4:26 AM 19 replies 2,175 viewsPage 4 of 4
VendorMark
Senior Member
3,456
14,567
Jan 2024
Texas
Online
Feb 4, 2024 at 8:49 AM#16

Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

That is the short version; the long version is somebody else's post.

21 19DebRD_ATL, KristenIndy, MarkLI_maint and 18 others
Reply Quote Save Share Report
pete_RVA
Member
178
890
Dec 2024
Richmond, VA
Feb 5, 2024 at 8:10 AM#17
SleepDoc_PDX said:
Shipping damage protocol for vendor vetting orders: if your package arrives with visible damage, temperature excursion, or broken vials: Photograph…

Coming at SleepDoc_PDX’s question from a different direction. They are not contradictory, they measure different things, and this is the single most common misreading of a certificate. Purity is a relative area measurement: the main peak as a percentage of total peak area in the chromatogram. Content is an absolute mass measurement against a reference standard. A vial can be 99% pure and contain 6.1mg — pure material, overfilled — or 99% pure and contain 3mg, which is pure material and a short fill. Purity tells you what fraction of what is there is the right molecule; content tells you how much of it there is. You need both, and a certificate with only purity is telling you half the story.

Last edited: Feb 5, 2024 at 1:10 PM
22 20Dr.Martinez, mike_mod, SarahChen_PharmD and 19 others
Reply Quote Save Share Report
wendy_avl
Member
245
1,123
Oct 2024
Asheville, NC
Feb 6, 2024 at 7:30 AM#18

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

23 21TomTeleRx, DoseLogDan, SleepFixSam and 20 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
wanda_boise
Member
412
1,890
Aug 2024
Boise, ID
Feb 7, 2024 at 6:50 AM#19

A narrower follow-up, since the general answer is now clear:

Why two laboratories report different purity for the same batch, and which number to believe?

24 22nick_SD_fit, ben_calgary, patPC_UT and 21 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Feb 8, 2024 at 6:09 AM#20

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

Last edited: Feb 8, 2024 at 8:09 AM
46 19PurityPaulOR, MaxMetOK, MounjBrad and 43 others
Reply Quote Save Share Report

Similar Threads

HPLC vs UPLC for peptide purity — method comparison study18 replies
Mass spectrometry for peptide identity verification — ESI-MS guide7 replies
Endotoxin testing methods — LAL vs recombinant Factor C17 replies
Red flags on COAs — how to spot a fake certificate5 replies
USP reference standards for peptide verification — sourcing guide3 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register