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ForumsPharmacology & MechanismsGLP-1R desensitization — 12 month update Page 6

GLP-1R desensitization — 12 month update

WendyG_ATL Sat, Aug 16, 2025 at 8:18 AM 40 replies 1,750 viewsPage 6 of 8
claudia_zurich
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Aug 20, 2025 at 9:52 PM#26
Dr.GutHealth said:
Keep the original post as written when you update it, and add the correction underneath.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Last edited: Aug 21, 2025 at 3:52 AM
21 19emma_london, tammy_FL, Dr.LipidDallas and 18 others
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Dr.NutriCornell
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Aug 21, 2025 at 7:10 AM#27
Dr.GutHealth said:
Keep the original post as written when you update it, and add the correction underneath.

Thank you for spelling out the reasoning rather than just the conclusion. Adding it to my notes with a link back to this thread.

Last edited: Aug 21, 2025 at 9:10 AM
22 20Dr.SleepRoch, laura_annarbor, JenMemphis and 19 others
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rachel_ABQ
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Aug 21, 2025 at 4:27 PM#28

From the other side of the consultation, briefly. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

23 21AmyNC_wife, SkepticalSean, Dr.CardioMD and 20 others
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BethLabQueen
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Aug 22, 2025 at 1:44 AM#29
rachel_ABQ said:
It helps to ask what evidence would change your mind before you look at any.

Same pattern here, and in the same order.

24 22cory_ATX, lori_vegas, Dr.PulmRoch and 21 others
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WendyG_ATL
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Aug 22, 2025 at 11:01 AM#30

OP back with an update, since a thread like this is useless without one.

Closing this out: the trough rather than the peak explains the pattern I was seeing on day six, which I had been blaming on the vial.

46 19DebRD_ATL, KristenIndy, MarkLI_maint and 43 others
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