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ForumsCOA & Analytical TestingMass spectrometry for peptide identity verification — March 2026 Page 7

Mass spectrometry for peptide identity verification — March 2026

JakeBK_lifts Thu, Oct 31, 2024 at 6:08 AM 37 replies 2,134 viewsPage 7 of 8
josh_phd_bmore
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Nov 29, 2024 at 6:34 PM#31

Adding the numbers, since they settle part of this. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

39 12NurseKim_ATL, paul_denver, TinaHashiRN and 36 others
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DoseLogDan
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Feb 2025
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Dec 1, 2024 at 1:16 PM#32

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

40 13Dr.AddMedPHL, newstart_MO, mia_MS2 and 37 others
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CarlaRPh_TPA
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Dec 3, 2024 at 7:57 AM#33
josh_phd_bmore said:
One practical note: write down what you did and when, before you need it.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Dec 3, 2024 at 11:57 AM
41 14BrianDallas92, labquiet_amy, emily_PDX and 38 others
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Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

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paige_pharma
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Sep 2024
Omaha, NE
Dec 5, 2024 at 2:37 AM#34
josh_phd_bmore said:
One practical note: write down what you did and when, before you need it.

josh_phd_bmore has the substance of this right. The condition it depends on is worth stating. Yes, and the corollary is less popular: if the reasoning holds, it also holds where it produces an answer we do not like.

42 15lisa_labSD, adam_van, Dr.SurgeonPGH and 39 others
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Dr.PathRoch
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Rochester, MN
Dec 6, 2024 at 9:16 PM#35
josh_phd_bmore said:
One practical note: write down what you did and when, before you need it.

This answered a question I did not know how to ask.

43 16Dr.MetabolicMD, RetaRick_CA, JenPlateau and 40 others
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