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ForumsCOA & Analytical TestingMass spectrometry for peptide identity verification — March 2026 Page 6

Mass spectrometry for peptide identity verification — March 2026

hannah_MT Sat, Jul 12, 2025 at 7:00 AM 26 replies 1,892 viewsPage 6 of 6
tampaLisa73
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Tampa, FL
Jul 21, 2025 at 10:57 AM#26
BiostatsBrad said:
One habit that pays for itself: post the method alongside the number.

Genuinely useful, thank you. I had the facts and not the framework. I will report back once I have actually tried it.

Last edited: Jul 21, 2025 at 11:57 AM
30 3RunnerRach, TrialNerd_Beth, HPLC_Greg and 27 others
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Dr.ReproEndo
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Jul 21, 2025 at 11:18 PM#27

From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

31 4andrew_nyc, Dr.EndoEP, GraceAZ_72 and 28 others
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Dr.GastroMayo
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Mayo Clinic, MN
Jul 22, 2025 at 11:38 AM#28
Dr.ReproEndo said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Second this.

32 5COA_Karl, MikeFit_NJ, InsuranceTom and 29 others
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cory_ATX
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Austin, TX
Jul 22, 2025 at 11:58 PM#29
Dr.ReproEndo said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Coming at Dr.ReproEndo’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

33 6Dr.PathRoch, mona_PHX, andrew_nyc and 30 others
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hannah_MT
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Bozeman, MT
Jul 23, 2025 at 12:18 PM#30

Closing the loop on my own question.

Follow-up — I put something in the gap where food used to be rather than waiting for the gap to close on its own. That was the part nobody told me.

5 3SleepFixSam, PurityPaulOR, MaxMetOK and 2 others
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