Amino acid analysis for peptide identity — looking for input

PharmD_Rodriguez said:

The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

Agreed, and for anyone with an eating-disorder history this needs a clinician in the loop rather than a forum. The same drug can be therapeutic in binge-eating disorder and actively harmful in a restrictive disorder.

pat_auckland said:

True, and anyone with reduced kidney function needs that target set by a clinician rather than a forum.

Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.

PharmD_Rodriguez said:

The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.

Pushing back on PharmD_Rodriguez here. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Correct me if the detail matters more than I have assumed.

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. No action needed from anybody.