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ForumsRetatrutide & Triple AgonistsRetatrutide Phase 2 dose-response analysis — need advice Page 6

Retatrutide Phase 2 dose-response analysis — need advice

SarahChen_PharmD Wed, Sep 11, 2024 at 8:40 PM 55 replies 2,123 viewsPage 6 of 11
nick_newbie
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Sep 16, 2024 at 4:55 AM#26
stefan_berlin said:
Worth stating the units and the reference range whenever you post a number here.

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

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CarlaRPh_TPA
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Sep 16, 2024 at 4:10 PM#27
stefan_berlin said:
Worth stating the units and the reference range whenever you post a number here.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

Worth separating that from the trial evidence, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

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A1cHero_PHX
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Sep 17, 2024 at 3:25 AM#28
stefan_berlin said:
Worth stating the units and the reference range whenever you post a number here.

This answered a question I did not know how to ask.

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paige_pharma
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Sep 17, 2024 at 2:40 PM#29

Adding the clinical framing, because it changes how the question reads. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Last edited: Sep 17, 2024 at 3:40 PM
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SarahChen_PharmD
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Sep 18, 2024 at 1:54 AM#30

OP back with an update, since a thread like this is useless without one.

Update — my curve sits below the published mean and the explanation is that the trial arm had support I do not have. That was reassuring rather than otherwise.

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