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ForumsRetatrutide & Triple AgonistsRetatrutide Phase 2 dose-response analysis — need advice Page 4

Retatrutide Phase 2 dose-response analysis — need advice

SarahChen_PharmD Wed, Sep 11, 2024 at 8:40 PM 55 replies 2,123 viewsPage 4 of 11
anna.melb_AU
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Sep 13, 2024 at 2:58 AM#16

From the other side of the consultation, briefly. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Ask again with the specifics and you will get a better answer than this one.

33 6DerekSJ_a1c, paige_pharma, emma_london and 30 others
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Dr.SleepRoch
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Sep 13, 2024 at 6:30 AM#17

A narrower follow-up, since the general answer is now clear:

How to read a result like this without either dismissing it or over-reading it, since the summaries all read like press releases?

34 7kim_atl_prep, sarah_TO, wendy_avl and 31 others
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PedsEndoPhilly
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Sep 13, 2024 at 10:02 AM#18
anna.melb_AU said:
Start from the measurement rather than the conclusion.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

35 8jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 32 others
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WendyG_ATL
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Sep 13, 2024 at 1:34 PM#19
anna.melb_AU said:
Start from the measurement rather than the conclusion.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

36 9AttorneyGrant, DebRD_ATL, KristenIndy and 33 others
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Admin
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Sep 13, 2024 at 5:06 PM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. No action needed from anybody.

Last edited: Sep 13, 2024 at 9:06 PM
8 6PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 5 others
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