One thing that is still open after Dr.ObesityLA’s answer:
Did your prescriber agree with that reading, and if not what was their objection?
One thing that is still open after Dr.ObesityLA’s answer:
Did your prescriber agree with that reading, and if not what was their objection?
FDA_TrackerJim said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
FDA_TrackerJim said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
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View ResultsFDA_TrackerJim said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.
Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.