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ForumsPublic SquareAmylin co-agonism: CagriSema REDEFINE results and implications — 6 month update Page 4

Amylin co-agonism: CagriSema REDEFINE results and implications — 6 month update

Dr.SportsMedIN Wed, Apr 16, 2025 at 10:44 AM 31 replies 1,645 viewsPage 4 of 7
WendyG_ATL
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Apr 18, 2025 at 5:05 AM#16
PeptideChemSF said:
The mechanism and the magnitude are separate questions.

Same pattern here, and in the same order. I had assumed I was the exception until I read this.

Last edited: Apr 18, 2025 at 6:05 AM
30 3Dr.SurgeonPGH, rachel_ABQ, traveltech_sara and 27 others
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FDA_TrackerJim
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Apr 18, 2025 at 9:18 AM#17

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

31 4Admin, Dr.Martinez, mike_mod and 28 others
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RegAffairsDC
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Apr 18, 2025 at 1:32 PM#18

One thing that is still open after TrialTracker_MD’s answer:

Was that from a primary source or from a summary of one?

Last edited: Apr 18, 2025 at 3:32 PM
32 5hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 29 others
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SleepFixSam
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Apr 18, 2025 at 5:46 PM#19
FDA_TrackerJim said:
Practical: whatever you change, write down the date and the reason.

Pushing back on FDA_TrackerJim here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Last edited: Apr 18, 2025 at 7:46 PM
33 6denise_HTX, raj_cambridge, ingrid_STO and 30 others
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Admin
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Apr 18, 2025 at 10:00 PM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Tagging this one for the weekly digest.

5 3PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 2 others
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