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ForumsCardiovascular OutcomesLp(a) on GLP-1 agonists — March 2026

Lp(a) on GLP-1 agonists — March 2026

quinn_sf Thu, Apr 16, 2026 at 6:38 PM 19 replies 901 viewsPage 1 of 4
quinn_sf
Member
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Jun 2024
San Francisco, CA
Apr 16, 2026 at 6:38 PM#1

Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

So the question, as narrowly as I can put it: whether an unchanged LDL-C alongside a large triglyceride fall is a good result or a bad one, because ApoB and LDL-C seem to be telling different stories.

Numbers rather than impressions, if you have them.

39 9tane_welly, Dr.PathRoch, mona_PHX and 36 others
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TirzTom
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Feb 2024
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Apr 16, 2026 at 6:44 PM#2
quinn_sf said:
Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

Comprehensive lipid panel update relevant to the lipid panel:

MarkerBaseline6 Months12 MonthsReference
Total Cholesterol233218178<200
LDL16813898<100
HDL415660>40
Triglycerides213168118<150
LDL-P14731223873<1000

The triglyceride drop is the most impressive. My cardiologist reduced my statin dose based on these results.

38 8tom_AK, josh_phd_bmore, roxy_nash and 35 others
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NurseKim_ATL
Senior Member
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Feb 2024
Atlanta, GA
Apr 16, 2026 at 6:50 PM#3
TirzTom said:
Comprehensive lipid panel update relevant to the lipid panel: Marker Baseline 6 Months 12 Months Reference Total Cholesterol 233 218 178 <200 LDL…

Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data:

CategoryMarkerBeforeAfter 10moChange
MetabolicA1C7.4%5.6%⬇️ 1.6%
MetabolicFasting Glucose12287⬇️ 27
LipidsLDL15094⬇️ 42
LipidsTriglycerides222112⬇️ 92
InflammationhsCRP7.51.0⬇️ 6.0

Every single metabolic marker improved. This is why I'm a believer in this therapy.

37 7ingrid_STO, pete_nash, hank_denver and 34 others
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BiostatsBrad
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Jul 2024
Durham, NC
Apr 16, 2026 at 6:56 PM#4
quinn_sf said:
Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

36 6james_edin, FranDenver, Dr.BariatricHTX and 33 others
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pat_auckland
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Jun 2024
Auckland, NZ
Apr 16, 2026 at 7:26 PM#5

Clinical perspective, offered as context rather than as advice.

Tracking labs for the lipid panel — here's the panel I get every 3 months and why:

  • CMP: glucose, electrolytes, kidney function, liver enzymes
  • Lipid panel: total cholesterol, LDL, HDL, triglycerides
  • A1C: 3-month glucose average
  • hsCRP: inflammatory marker
  • CBC: blood counts, anemia screening
  • B12, folate, iron: nutritional deficiency screening
  • TSH, free T4: thyroid monitoring
  • Lipase: pancreatic safety check

Total cost with insurance: about $31 copay. Without insurance, request cash-pay pricing from Quest/Labcorp — usually $156.

35 5dan_philly, MeganSA_TX, LarryQC_SD and 32 others
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