TirzTom said:Comprehensive lipid panel update relevant to the lipid panel: Marker Baseline 6 Months 12 Months Reference Total Cholesterol 233 218 178 <200 LDL…
Careful with treating an unchanged LDL-C as a failure. If ApoB and triglycerides both fell, the particle picture improved regardless of what the calculated LDL says.
quinn_sf said:Trying to work out whether my panel improved or merely rearranged itself, because two of the numbers went the wrong way.
Omega-3 index improvement on the lipid panel: often overlooked but my omega-3 index went from 3.5% to 7.5% over 8 months. I supplemented with 2g EPA+DHA daily.
This matters because omega-3s are anti-inflammatory and cardioprotective, complementing the GLP-1 benefits. Target omega-3 index is >8%. Combined with the triglyceride reduction from the medication, my lipid profile is the best it's been in decades.
Dr.PainCLE said:Careful with treating an unchanged LDL-C as a failure.
Advanced lipoprotein testing on the lipid panel — going beyond standard lipid panel:
| Marker | Baseline | Month 8 | Clinical Meaning |
|---|---|---|---|
| LDL-P | 1639 | 939 | Particle count (more precise than LDL-C) |
| Small dense LDL | 69% | 35% | Atherogenic pattern |
| Remnant cholesterol | 43 | 18 | Triglyceride-rich lipoproteins |
| oxLDL | 84 | 47 | Oxidative stress marker |
The shift from small dense to large buoyant LDL is particularly important — it represents a fundamental change in the atherogenic profile.
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View ResultsA narrower follow-up, since the general answer is now clear:
Did your prescriber agree with that reading, and if not what was their objection?
OP back with an update, since a thread like this is useless without one.
Reporting back for the archive rather than for the thread: I did the narrow version of what was suggested, gave it the full interval, and it settled. Posting it because threads without a follow-up are half a thread.