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ForumsPharmacology & MechanismsBiased agonism at GLP-1R — 12 month update Page 4

Biased agonism at GLP-1R — 12 month update

pam_columbus Tue, Dec 17, 2024 at 6:06 AM 52 replies 2,746 viewsPage 4 of 11
pat_auckland
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Jan 6, 2025 at 12:07 PM#16

Adding the clinical framing, because it changes how the question reads. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

Last edited: Jan 6, 2025 at 4:07 PM
6 4NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 3 others
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labquiet_amy
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Jan 9, 2025 at 10:17 AM#17
pat_auckland said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Adding a me-too, because a thread of one person's experience is not much use.

7 5HPLC_Greg, LibrarianMeg, bri_stats and 4 others
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KevinCompounds
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Jan 12, 2025 at 8:25 AM#18
pat_auckland said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Adding the part of the answer the thread has not reached. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Last edited: Jan 12, 2025 at 10:25 AM
8 6MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 5 others
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bri_stats
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Jan 15, 2025 at 6:32 AM#19

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

I would rather be corrected than agreed with, if it comes to it.

9 7JessicaM_2024, TomFromTexas, mike.trainer_LA and 6 others
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Admin
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Jan 18, 2025 at 4:37 AM#20

Moderator note: a couple of off-topic posts removed.

Last edited: Jan 18, 2025 at 8:37 AM
31 4PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 28 others
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