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Evidence-based GLP-1 & peptide discussion since 2023
ForumsBuyer Beware⚠ Fake COAs — March 2026 Page 4

⚠ Fake COAs — March 2026

Dr.CardioMD Thu, Oct 31, 2024 at 8:56 AM 54 replies 3,020 viewsPage 4 of 11
lisa_labSD
Member
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Oct 2024
San Diego, CA
Nov 4, 2024 at 12:19 PM#16

Clinical perspective, offered as context rather than as advice.

Third-party testing services for certificates of analysis besides Janoshik:

  • Janoshik: Gold standard for peptide community, ~$153, 10-14 day turnaround
  • Valitech: US-based, ISO 17025 accredited, ~$233
  • Eurofins: Full pharmaceutical testing suite, more expensive but comprehensive
  • ChemTox: Basic identity and purity testing, ~$103

Janoshik is the community standard but any ISO-accredited analytical lab can verify peptide identity and purity. The key is independence — don't rely solely on the vendor's own testing.

20 18stefan_berlin, Dr.EM_Chicago, pete_RVA and 17 others
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tammy_FL
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Nov 2024
Tampa, FL
Nov 5, 2024 at 1:11 AM#17
lisa_labSD said:
Third-party testing services for certificates of analysis besides Janoshik: Janoshik: Gold standard for peptide community, ~$153, 10-14 day turnaround…

COA red flags for certificates of analysis — here's what to look for when reviewing a Certificate of Analysis:

  • No HPLC data: If there's no chromatography graph, it's not a real COA
  • Exact 100% purity: Suspicious — real testing always shows slight variation
  • No batch number: Can't trace back to specific production
  • No endotoxin testing: For injectables, this is essential
  • Template looks like it was made in Word: Professional labs have standardized formats

I have seen fake COAs that are literally photoshopped. Always verify independently if possible.

21 19alex_tucson, kevin_tulsa, Dr.PainCLE and 18 others
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Dr.SportsMedIN
Senior Member
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6,789
Feb 2024
Indianapolis, IN
Nov 5, 2024 at 2:03 PM#18
lisa_labSD said:
Third-party testing services for certificates of analysis besides Janoshik: Janoshik: Gold standard for peptide community, ~$153, 10-14 day turnaround…

HPLC results interpretation for certificates of analysis: when you get your Janoshik report back, here's what the numbers mean:

  • Purity %: Should be >97%. Below 95% is concerning.
  • Retention time: Should match reference standard for the peptide
  • Related substances: Degradation products should be <2% total
  • Single impurity: No individual impurity should exceed 1%

My last batch: 99.2% purity, 0.2% total related substances. Clean chromatogram with single sharp peak at expected retention time. Exactly what you want to see.

22 20adam_van, Dr.SurgeonPGH, rachel_ABQ and 19 others
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Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
Dr.NephBHM_UK
Member
456
2,123
Jun 2024
Birmingham, UK
Nov 6, 2024 at 2:55 AM#19
lisa_labSD said:
Third-party testing services for certificates of analysis besides Janoshik: Janoshik: Gold standard for peptide community, ~$153, 10-14 day turnaround…

Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.

23 21SurmountFan_IN, PeptideChemSF, A1cHero_PHX and 20 others
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Admin
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Oct 2023
Online
Nov 6, 2024 at 3:47 PM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out. Report rather than reply if it drifts again.

45 18PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 42 others
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