Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Dr.GastroMayo said:The mechanism and the magnitude are separate questions.
This matches mine closely enough to be worth saying so out loud. Nothing to add that would improve it.
Dr.GastroMayo said:The mechanism and the magnitude are separate questions.
Coming at Dr.GastroMayo’s question from a different direction. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Happy to go further on any of that.
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Browse GL BiochemAdding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
One thing that is still open after Dr.GastroMayo’s answer:
Did your prescriber agree with that reading, and if not what was their objection?