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ForumsProgress & Lab ResultsHas anyone dealt with one hundred pounds down lets gooo?

Has anyone dealt with one hundred pounds down lets gooo?

DanielChem_CHI Tue, Apr 15, 2025 at 5:09 PM 25 replies 1,966 viewsPage 1 of 5
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DanielChem_CHI
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Apr 15, 2025 at 5:09 PM#1

Read the primary source rather than the write-up and the two do not agree, so here is what is actually in it.

Most reported plateaus are not plateaus. Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well inside the noise band. Before concluding anything, look at a rolling weekly average over at least four weeks and at a tape measure, because recomposition shows up in circumference before it shows up in weight. Then track intake honestly for a week: appetite suppression fades unevenly, and intake creeping back up is the single commonest cause.

Where I think it is weakest: the subgroup findings are the part I trust least — with enough subgroups something is always significant, and these were not all pre-registered.

The question I want answered is how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything. Practical detail welcome, however dull — the duller the better.

Note on sourcing:
Figures above are from the primary publication rather than the press summary. If a number here disagrees with one you have, post yours and we will work out which of us is reading a secondary source.
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LabKate
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Apr 15, 2025 at 5:38 PM#2
DanielChem_CHI said:
Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well…

Plateau breaking story with a stall: I stalled at 195 lbs for 7 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: a brief dose increase followed by return to maintenance. Lost 8 lbs in the next 3 weeks. Plateaus are temporary — they always break if you stay consistent.

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RetaRick_CA
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Apr 15, 2025 at 6:07 PM#3
DanielChem_CHI said:
Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well…

This is where I part company with the consensus forming above. The "it is your intake" reflex here gets tiring. Some people genuinely stop responding at a dose that worked, and telling them to track harder when they have already tracked is how people stop posting.

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GenomicsKate
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Apr 15, 2025 at 6:36 PM#4

Short answer first, then the reasoning. Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body. A body 20kg lighter needs meaningfully fewer calories at rest and less to move, so the deficit that produced the first phase is arithmetically smaller now. The options are the honest ones — increase the deficit slightly, increase activity, or accept the new plateau — and escalating the dose is only one of them.

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mike_mealprep
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Apr 15, 2025 at 9:15 PM#5
LabKate said:
Plateau breaking story with a stall: I stalled at 195 lbs for 7 weeks.

This is my experience too, for whatever a second data point is worth.

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