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ForumsExercise & Body CompositionCreatine loading vs maintenance on GLP-1 — my results so far Page 2

Creatine loading vs maintenance on GLP-1 — my results so far

DerekSJ_a1c Tue, Jul 9, 2024 at 7:47 AM 45 replies 2,756 viewsPage 2 of 9
dave_SLC
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Jul 9, 2024 at 12:27 PM#6

Adding the numbers, since they settle part of this. If you are tracking this properly: same scanner, same time of day, same hydration, at least six months apart, and read grip strength or a lift number alongside it. Function is the outcome; the scan is the proxy.

18 13mike_mealprep, NicoleRaleigh, james_edin and 15 others
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DadBodDave
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Jul 9, 2024 at 2:17 PM#7

One thing that is still open after hans_munich’s answer:

Whether extending the interval works as well as reducing the dose, since they are not the same intervention pharmacologically?

Last edited: Jul 9, 2024 at 5:17 PM
17 12JenMemphis, pat_auckland, Dr.GastroMayo and 14 others
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TinaHashiRN
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Jul 9, 2024 at 4:07 PM#8
dave_SLC said:
If you are tracking this properly: same scanner, same time of day, same hydration, at least six months apart, and read grip strength or a lift number…

Coming at dave_SLC’s question from a different direction. The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0 g/kg of reference body weight, and not making the deficit larger than the training can support. Cardio does not protect lean mass and in a deep deficit competes with recovery.

Worth separating that from lean-mass preservation, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Last edited: Jul 9, 2024 at 10:07 PM
16 11Dr.Martinez, mike_mod, SarahChen_PharmD and 13 others
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DerekSJ_a1c
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Jul 9, 2024 at 5:57 PM#9

Reporting back.

I went to a lower dose rather than a longer interval on the strength of the trough argument in this thread, and the difference in how even it feels is obvious.

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mark_tokyo
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Jul 10, 2024 at 2:45 AM#10
TinaHashiRN said:
The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0…

Agreed on the ranges, with the condition that a single DEXA is not a measurement, it is one draw from a distribution. Hydration status moves the lean compartment by a kilogram or more between scans, so any comparison of scans done at different times of day or different hydration states is noise.

11 9TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 8 others
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