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ForumsExercise & Body CompositionPowerlifting on GLP-1 — my results so far Page 4

Powerlifting on GLP-1 — my results so far

PedsEndoPhilly Wed, Sep 10, 2025 at 4:40 PM 36 replies 1,892 viewsPage 4 of 8
Dr.CardioMD
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Sep 14, 2025 at 3:31 PM#16
PeptideChemSF said:
lean mass + resistance training is the combo.

Same experience, arrived at from the opposite direction.

Last edited: Sep 14, 2025 at 9:31 PM
22 20kim_atl_prep, sarah_TO, wendy_avl and 19 others
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amsterdam_pete
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Sep 15, 2025 at 1:09 AM#17
dan_philly said:
Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…

Thank you for spelling out the reasoning rather than just the conclusion.

23 21ZaraB_AL, JakeSmashed95, NauseaFreeNow and 20 others
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newstart_MO
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Sep 15, 2025 at 10:47 AM#18

Adding the clinical framing, because it changes how the question reads.

Sharing my comprehensive lab data relevant to lean mass:

BiomarkerBaselineMonth 3Month 6Month 9
Weight (lbs)280230220210
A1C (%)7.56.06.15.2
hsCRP (mg/L)5.04.01.50.6
Triglycerides180180140100

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/week, protein 1.2g/kg/day.

The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.

24 22HPLC_Greg, LibrarianMeg, bri_stats and 21 others
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kevin_tulsa
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Tulsa, OK
Sep 15, 2025 at 8:25 PM#19
newstart_MO said:
Sharing my comprehensive lab data relevant to lean mass: Biomarker Baseline Month 3 Month 6 Month 9 Weight (lbs) 280 230 220 210 A1C (%) 7.5 6.0 6.1…

Can confirm. Same sequence, different timescale. Nothing to add that would improve it.

25 23quinn_sf, NurseLeah_Nash, gary_naperville and 22 others
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mike_mod
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Sep 16, 2025 at 6:03 AM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Tagging this one for the weekly digest.

47 20PurityPaulOR, MaxMetOK, MounjBrad and 44 others
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