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ForumsMASH / Liver DiseaseAlcohol + MASH + GLP-1 — July 2024 Page 3

Alcohol + MASH + GLP-1 — July 2024

carlos_SATX Sun, Oct 19, 2025 at 3:58 PM 44 replies 1,456 viewsPage 3 of 9
julia.endo
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Oct 23, 2025 at 2:43 PM#11
LibrarianMeg said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

Last edited: Oct 23, 2025 at 8:43 PM
20 18anna.melb_AU, mark_tokyo, hans_munich and 17 others
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BiostatsBrad
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Oct 25, 2025 at 10:53 AM#12
JennaRN said:
Agreed, and ALT falling is not the same as fibrosis improving.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Printing the relevant bit and taking it with me.

Last edited: Oct 25, 2025 at 11:53 AM
21 19Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 18 others
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DebRD_ATL
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Oct 27, 2025 at 7:02 AM#13
LibrarianMeg said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

I read this differently from LibrarianMeg, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

22 20SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 19 others
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TirzTom
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Oct 29, 2025 at 3:10 AM#14

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

23 21SandraNC_45, Dr.EndoIndy, tom_AK and 20 others
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mike_mod
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Oct 30, 2025 at 11:17 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out.

24 22PurityPaulOR, MaxMetOK, MounjBrad and 21 others
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