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ForumsMASH / Liver DiseaseHas anyone dealt with de novo lipogenesis reduction on glp-1? Page 7

Has anyone dealt with de novo lipogenesis reduction on glp-1?

NurseLeah_Nash Tue, Nov 18, 2025 at 1:33 AM 34 replies 1,698 viewsPage 7 of 7
james_edin
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Nov 28, 2025 at 5:18 AM#31
NurseLeah_Nash said:
Nothing dramatic to report, which is the report.

This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

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mike_mealprep
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Nov 28, 2025 at 1:46 PM#32
NurseLeah_Nash said:
Nothing dramatic to report, which is the report.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

Happy to go further on any of that.

Last edited: Nov 28, 2025 at 7:46 PM
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pete_manc_UK
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Nov 28, 2025 at 10:14 PM#33
NurseLeah_Nash said:
Nothing dramatic to report, which is the report.

That reframing is the part I needed. Adding it to my notes with a link back to this thread.

Last edited: Nov 29, 2025 at 4:14 AM
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Dr.SportsMedIN
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Nov 29, 2025 at 6:41 AM#34

Clinical perspective, offered as context rather than as advice. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

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COA_Karl
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Nov 29, 2025 at 3:08 PM#35
Dr.SportsMedIN said:
It is worth asking what the claim would look like if it were false.

Mine went the same way, slower. The detail I would add is minor and it is already implied above.

Last edited: Nov 29, 2025 at 4:08 PM
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