One thing that is still open after traveltech_sara’s answer:
What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?
wanda_boise said:I did go to 2.4mg in the end, and the honest report is that it bought me less than the step before it and cost me two bad weeks.
I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.
wanda_boise said:I did go to 2.4mg in the end, and the honest report is that it bought me less than the step before it and cost me two bad weeks.
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.
Correct me if the detail matters more than I have assumed.
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Browse GL Biochemwanda_boise said:I did go to 2.4mg in the end, and the honest report is that it bought me less than the step before it and cost me two bad weeks.
Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.
Clinical perspective, offered as context rather than as advice. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.