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ForumsMASH / Liver DiseaseDe novo lipogenesis reduction on GLP-1 — mechanistic hepatology Page 4

De novo lipogenesis reduction on GLP-1 — mechanistic hepatology

MASHdoc_SA Mon, Jun 1, 2026 at 1:48 AM 17 replies 523 viewsPage 4 of 4
fiona_VT
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Jun 3, 2026 at 1:33 AM#16
claudia_zurich said:
Start from the measurement rather than the conclusion.

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

Last edited: Jun 3, 2026 at 2:33 AM
8 6mark_tokyo, hans_munich, jason_sac26 and 5 others
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CanadaChris
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Jun 3, 2026 at 5:37 AM#17
raj_cambridge said:
Practical: whatever you change, write down the date and the reason.

I read this differently from raj_cambridge, on substance rather than tone. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Jun 3, 2026 at 11:37 AM
9 7stefan_berlin, Dr.EM_Chicago, pete_RVA and 6 others
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mike_mealprep
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Jun 3, 2026 at 9:41 AM#18
raj_cambridge said:
Practical: whatever you change, write down the date and the reason.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

Last edited: Jun 3, 2026 at 3:41 PM
10 8Dr.AddMedPHL, newstart_MO, mia_MS2 and 7 others
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mike.trainer_LA
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Jun 3, 2026 at 1:45 PM#19
raj_cambridge said:
Practical: whatever you change, write down the date and the reason.

Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.

Last edited: Jun 3, 2026 at 5:45 PM
11 9LeilaHI, marcus_mpls, DeniseRN_TPA and 8 others
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mike_mod
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Jun 3, 2026 at 5:49 PM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here.

33 6PurityPaulOR, MaxMetOK, MounjBrad and 30 others
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