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ForumsSemaglutide (Ozempic / Wegovy)Compounded semaglutide stability data — temperature and light sensitivity Page 4

Compounded semaglutide stability data — temperature and light sensitivity

kate.chem Sun, Jun 7, 2026 at 9:34 PM 16 replies 290 viewsPage 4 of 4
Dr.ReproEndo
Senior Member
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Scottsdale, AZ
Jun 8, 2026 at 2:44 PM#16
Dr.AddMedPHL said:
Storage question about storage and cold: my pen was left out of the fridge for 8 hours.

Adding a me-too, because a thread of one person's experience is not much use. I had assumed I was the exception until I read this.

26 24mona_PHX, andrew_nyc, Dr.EndoEP and 23 others
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TinaHashiRN
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Sep 2024
Raleigh, NC
Jun 8, 2026 at 4:31 PM#17
VendorMark said:
Cold chain shipping for storage and cold: my last order arrived with the cold pack completely melted and the vial at room temperature.

Bookmarking. The distinction being drawn above is the one nobody else makes. I will report back once I have actually tried it.

27 0mike_mod, SarahChen_PharmD, sarah.morrison and 24 others
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Dr.GutHealth
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Jun 8, 2026 at 6:19 PM#18

From the other side of the consultation, briefly.

Storage best practices for compounded storage and cold:

  • Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months
  • Reconstituted vials: refrigerate, use within 28 days
  • Pre-filled pens: refrigerate until first use, then room temp OK for 28 days
  • Never freeze reconstituted peptides — ice crystals damage the protein
  • Protect from light — store in original box or wrap in foil

When in doubt, refrigerate. Temperature abuse is the #1 cause of reduced potency in compounded peptides.

28 1jennifer_SEA, tyler_CSCS, VanRx_Mike and 25 others
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Dr.NateNeph
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Houston, TX
Jun 8, 2026 at 8:06 PM#19
Dr.GutHealth said:
Storage best practices for compounded storage and cold: Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months Reconstituted…

Mine went the same way, slower.

Last edited: Jun 8, 2026 at 10:06 PM
29 2B12Beth, RickReta_CO, PharmHunterJen and 26 others
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Admin
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Jun 8, 2026 at 9:53 PM#20

Moderator note: a couple of off-topic posts removed.

1 24PeptideSynthNJ
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