Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
paige_pharma said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Mine went the same way, slower. Nothing to add that would improve it.
paige_pharma said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
There is a second half to this that has not been said yet. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.
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View ResultsAdding the numbers, since they settle part of this. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.
OP back with an update, since a thread like this is useless without one.
Coming back a few months on. It held. Nothing dramatic to report, which is the report.