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ForumsClinical Trials & ResearchSo when is the pill version actually coming? Tired of needles — looking for input

So when is the pill version actually coming? Tired of needles — looking for input

RegAffairsDC Mon, Dec 22, 2025 at 6:35 PM 12 replies 1,142 viewsPage 1 of 3
RegAffairsDC
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Dec 22, 2025 at 6:35 PM#1

The fatigue arrived at about week six and has not shifted since, and I cannot tell whether it is the drug, the deficit or something I should have tested by now.

What would genuinely help is knowing whether the fatigue is a direct drug effect or simply the caloric deficit, because the answer changes what you do about it.

Happy to be told the question itself is wrong.

1 4amy_econ_NJ
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mike.trainer_LA
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Dec 22, 2025 at 6:49 PM#2

Short answer first, then the reasoning. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

2 5newstart_MO, mia_MS2
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PharmD_Rodriguez
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Dec 22, 2025 at 7:03 PM#3
mike.trainer_LA said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

3 6robert_kc, dan_philly, MeganSA_TX
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raj_cambridge
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Dec 22, 2025 at 7:17 PM#4
RegAffairsDC said:
The fatigue arrived at about week six and has not shifted since, and I cannot tell whether it is the drug, the deficit or something I should have…

Same experience, arrived at from the opposite direction. Nothing to add that would improve it.

Last edited: Dec 22, 2025 at 8:17 PM
4 7PharmHunterJen, TomTeleRx, DoseLogDan and 1 other
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Dr.EndoEP
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Dec 22, 2025 at 8:33 PM#5

From the other side of the consultation, briefly. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

5 8LindaRN_retired, tommy_boulder, hyun_seoul and 2 others
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