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ForumsCardiovascular OutcomesHas anyone dealt with apob reduction on tirzepatide? Page 6

Has anyone dealt with apob reduction on tirzepatide?

tampaLisa73 Sat, Apr 26, 2025 at 11:05 AM 41 replies 2,416 viewsPage 6 of 9
RegAffairsDC
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Jul 6, 2025 at 12:57 PM#26
FDA_TrackerJim said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

42 15amy_econ_NJ, bbq_ray_KC, oliver_london and 39 others
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hyun_seoul
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Seoul, KR
Jul 15, 2025 at 6:33 PM#27
FDA_TrackerJim said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

Last edited: Jul 15, 2025 at 10:33 PM
43 16GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 40 others
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NicoleRaleigh
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Jul 25, 2025 at 12:15 AM#28
FDA_TrackerJim said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

This answered a question I did not know how to ask. I will report back once I have actually tried it.

44 17COA_Karl, MikeFit_NJ, InsuranceTom and 41 others
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MASHdoc_SA
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Aug 3, 2025 at 6:02 AM#29

Clinical perspective, offered as context rather than as advice. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

That is the short version; the long version is somebody else's post.

45 18LabKate, kate.chem, DataDave and 42 others
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tampaLisa73
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Aug 12, 2025 at 11:54 AM#30

OP back with an update, since a thread like this is useless without one.

Closing this out. What actually changed my mind was the point about waiting for a trend instead of reading a single measurement, which is embarrassing in hindsight and worth saying anyway.

Last edited: Aug 12, 2025 at 12:54 PM
17 15TomFromTexas, mike.trainer_LA, sarah_nash92 and 14 others
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