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ForumsCompounding & FormulationPeptide oxidation and deamidation — November 2025 Page 7

Peptide oxidation and deamidation — November 2025

TrialTracker_MD Thu, May 30, 2024 at 5:10 AM 45 replies 2,266 viewsPage 7 of 9
james_edin
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Jun 5, 2024 at 5:52 AM#31

Adding the clinical framing, because it changes how the question reads. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

Last edited: Jun 5, 2024 at 7:52 AM
34 9mona_PHX, andrew_nyc, Dr.EndoEP and 31 others
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hans_munich
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Jun 5, 2024 at 2:19 PM#32
james_edin said:
The useful move here is to separate what is established from what is widely repeated.

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

33 8alex_tucson, kevin_tulsa, Dr.PainCLE and 30 others
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SaraMom3
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Jun 5, 2024 at 10:46 PM#33
james_edin said:
The useful move here is to separate what is established from what is widely repeated.

There is a second half to this that has not been said yet. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Last edited: Jun 6, 2024 at 2:46 AM
32 7KetoKyle, CanadaChris, ZaraB_AL and 29 others
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quinn_sf
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Jun 6, 2024 at 7:12 AM#34

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

31 6andrew_nyc, Dr.EndoEP, GraceAZ_72 and 28 others
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robert_kc
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Jun 6, 2024 at 3:38 PM#35

A narrower follow-up, since the general answer is now clear:

What would you measure differently if you were starting again?

30 5PharmHunterJen, TomTeleRx, DoseLogDan and 27 others
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