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ForumsCompounding & FormulationPeptide oxidation and deamidation — my results so far Page 2

Peptide oxidation and deamidation — my results so far

WendyG_ATL Fri, May 16, 2025 at 8:30 AM 12 replies 1,556 viewsPage 2 of 3
LabKate
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May 16, 2025 at 12:10 PM#6
DataDave said:
Resolution therefore closed the doors unevenly, and the asymmetry follows from the bulks lists.

I read this differently from DataDave, on substance rather than tone. A research-chemical supplier selling lyophilised powder labelled research use only is not compounding and is not claiming to. It is a different legal universe with no pharmacy oversight, no patient relationship and no content guarantee, and conflating the two in these threads helps nobody.

3 6JenMemphis, pat_auckland, Dr.GastroMayo
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jason_paloalto
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May 16, 2025 at 1:36 PM#7
WendyG_ATL said:
Two pharmacies quoted me last year, one describing itself as 503A and one as 503B, and I assumed 503B just meant bigger until both stopped within…

Price comparison for compounded supply across sources I've used:

SourceMonthly CostTypePurity Verified
Brand (Ozempic)$975FDA-approvedN/A (pharma)
503B Compounding$155cGMP compoundedYes (in-house)
503A Compounding$125Patient-specificVaries
Research peptide$40Not for human useOften Janoshik

I use the 503B option — best balance of quality, cost, and legality. The brand price is insane but insurance can help if you qualify.

Last edited: May 16, 2025 at 6:36 PM
4 7Dr.PathRoch, mona_PHX, andrew_nyc and 1 other
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pete_nash
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May 16, 2025 at 3:02 PM#8
LabKate said:
A research-chemical supplier selling lyophilised powder labelled research use only is not compounding and is not claiming to.

I have been on both brand and compounded, and in the context of compounded supply, my experience has been equivalent with both. The key is finding a reliable 503B pharmacy with independent testing.

5 8mike_mod, SarahChen_PharmD, sarah.morrison and 2 others
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lori_vegas
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May 16, 2025 at 4:28 PM#9

Following on from Dr.NephBHM_UK — and this may be the naive question:

Why a shortage listing created a legal pathway at all, since a shortage is a supply fact rather than a permission?

6 9tane_welly, Dr.PathRoch, mona_PHX and 3 others
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WendyG_ATL
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May 16, 2025 at 11:19 PM#10

Closing the loop on my own question.

The bulks-list asymmetry was the piece I had missed entirely. It explains why one of my two pharmacies is still arguing it can supply and the other simply stopped.

26 1DebRD_ATL, KristenIndy, MarkLI_maint and 23 others
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