Dr.EM_Chicago said:The version of this that has an answer is narrower than the version being asked.
Same pattern here, and in the same order. The detail I would add is minor and it is already implied above.
Dr.EM_Chicago said:The version of this that has an answer is narrower than the version being asked.
There is a second half to this that has not been said yet. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.
Worth separating that from semaglutide, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.
The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
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View ResultsOne thing that is still open after Dr.EM_Chicago’s answer:
How long did you give it before you decided it was working?
Dr.PeteFamMed said:Say what you would expect to see if you were wrong, before you look.
I read this differently from Dr.PeteFamMed, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.