🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOral sema absorption enhancer SNAC — anyone have experience? Page 3

Oral sema absorption enhancer SNAC — anyone have experience?

dave_SLC Thu, Apr 4, 2024 at 11:27 PM 55 replies 2,928 viewsPage 3 of 11
labquiet_amy
Senior Member
1,234
6,789
Mar 2024
Cambridge, MA
Apr 11, 2024 at 3:16 AM#11
LibrarianMeg said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.

31 6TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 28 others
Reply Quote Save Share Report
nick_SD_fit
Member
278
1,234
Sep 2024
San Diego, CA
Apr 11, 2024 at 6:47 PM#12
mike_mod said:
The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest.

Thank you for spelling out the reasoning rather than just the conclusion.

Last edited: Apr 11, 2024 at 8:47 PM
30 5Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 27 others
Reply Quote Save Share Report
hans_munich
Member
534
2,345
Jul 2024
Munich, DE
Apr 12, 2024 at 10:18 AM#13
LibrarianMeg said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

29 4Dr.LipidDallas, alex_tucson, kevin_tulsa and 26 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
PeptideChemSF
Senior Member
1,890
9,012
Jan 2024
San Francisco, CA
Apr 13, 2024 at 1:50 AM#14

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

28 3ricardo_MIA, BrianDallas92, labquiet_amy and 25 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Apr 13, 2024 at 5:22 PM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. No action needed from anybody.

Last edited: Apr 13, 2024 at 7:22 PM
27 2PurityPaulOR, MaxMetOK, MounjBrad and 24 others
Reply Quote Save Share Report

Similar Threads

Orforglipron Phase 3 ATTAIN-1 topline — oral non-peptide GLP-116 replies
Oral semaglutide 50mg (Rybelsus HD) — OASIS program results12 replies
Danuglipron BID dosing — Pfizer oral GLP-1 update7 replies
Oral vs injectable GLP-1: bioavailability and efficacy comparison5 replies
Orforglipron food interaction profile — no fasting requirement15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register