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ForumsCardiovascular OutcomesAnti-thrombotic properties of GLP-1 receptor activation Page 3

Anti-thrombotic properties of GLP-1 receptor activation

Dr.CardioMD Fri, Jun 5, 2026 at 5:54 AM 17 replies 252 viewsPage 3 of 4
nick_SD_fit
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Jun 6, 2026 at 1:07 AM#11
PharmD_Rodriguez said:
PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.

This answered a question I did not know how to ask. Taking it to my next appointment.

35 10SkepticalSean, Dr.CardioMD, EndoResFellow and 32 others
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BariatricNurseD
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Jun 6, 2026 at 8:10 AM#12

From the other side of the consultation, briefly. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

34 9roxy_nash, tony_orlando, Dr.NephBHM_UK and 31 others
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MikeFit_NJ
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Jun 6, 2026 at 3:15 PM#13
VanRx_Mike said:
I want to add the drug interaction perspective on the pharmacology.

This is where I part company with the consensus forming above. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

Last edited: Jun 6, 2026 at 6:15 PM
33 8DeniseRN_TPA, SandraNC_45, Dr.EndoIndy and 30 others
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HPLC_Greg
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Jun 6, 2026 at 10:19 PM#14

The figures, for anyone assembling their own picture. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Ask again with the specifics and you will get a better answer than this one.

32 7Dr.MetabolicMD, RetaRick_CA, JenPlateau and 29 others
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Admin
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Jun 7, 2026 at 5:24 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Report rather than reply if it drifts again.

31 6PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 28 others
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