🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesApoB reduction on tirzepatide — SURPASS lipid substudies Page 3

ApoB reduction on tirzepatide — SURPASS lipid substudies

LipidDoc_ATL Sat, Jun 6, 2026 at 1:31 AM 13 replies 243 viewsPage 3 of 3
rick_sfbay
Member
289
1,234
Jan 2025
San Francisco, CA
Jun 6, 2026 at 8:55 AM#11
Dr.CardioMD said:
The GIP arm is doing real work rather than padding the label.

Bookmarking. The distinction being drawn above is the one nobody else makes. I will report back once I have actually tried it.

30 5mike_mealprep, NicoleRaleigh, james_edin and 27 others
Reply Quote Save Share Report
sean_dublin
Member
212
890
Nov 2024
Dublin, IE
Jun 6, 2026 at 10:59 AM#12

Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Last edited: Jun 6, 2026 at 11:59 AM
29 4sean_dublin, hannah_MT, Dr.SportsMedIN and 26 others
Reply Quote Save Share Report
Dr.MetabolicMD
VIP Member
2,345
16,789
Jan 2024
Rochester, MN
Jun 6, 2026 at 1:03 PM#13
LindaRN_retired said:
ApoB is the more informative number and it is cheap.

Careful with treating an unchanged LDL-C as a failure. If ApoB and triglycerides both fell, the particle picture improved regardless of what the calculated LDL says.

Last edited: Jun 6, 2026 at 3:03 PM
28 3HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 25 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
josh_phd_bmore
Member
389
1,678
Jul 2024
Baltimore, MD
Jun 6, 2026 at 3:07 PM#14

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

27 2KarenAZ_mom, zoe_NC, Dr.ObesityLA and 24 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Jun 6, 2026 at 5:11 PM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Thread quality here is what the rules are for. Keep it up.

26 1PurityPaulOR, MaxMetOK, MounjBrad and 23 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register