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ForumsCardiovascular OutcomesGLP-1 and arterial inflammation — hsCRP and IL-6 reduction data Page 2

GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data

Dr.MetabolicMD Sun, Jun 7, 2026 at 6:29 PM 18 replies 410 viewsPage 2 of 4
BethLabQueen
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Jun 7, 2026 at 9:00 PM#6
Dr.MetabolicMD said:
ApoB is the more informative number and it is cheap.

Comprehensive lipid panel update relevant to the lipid panel:

MarkerBaseline6 Months12 MonthsReference
Total Cholesterol232197177<200
LDL14711797<100
HDL404754>40
Triglycerides25214797<150
LDL-P14521102852<1000

The triglyceride drop is the most impressive. My cardiologist reduced my statin dose based on these results.

5 0maya_sedona, stefan_berlin, Dr.EM_Chicago and 2 others
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CryptoCarl
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Jun 7, 2026 at 9:59 PM#7

One thing that is still open after Dr.SurgeonPGH’s answer:

How would you tell the difference between that and the alternative explanation?

4 24MariaRD, AussieAnna, BethLabQueen and 1 other
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BariatricNurseD
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Jun 7, 2026 at 10:58 PM#8
BethLabQueen said:
Comprehensive lipid panel update relevant to the lipid panel: Marker Baseline 6 Months 12 Months Reference Total Cholesterol 232 197 177 <200 LDL…

Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data:

CategoryMarkerBeforeAfter 13moChange
MetabolicA1C8.0%5.5%⬇️ 1.2%
MetabolicFasting Glucose12590⬇️ 35
LipidsLDL173102⬇️ 45
LipidsTriglycerides245115⬇️ 95
InflammationhsCRP6.50.8⬇️ 5.0

Every single metabolic marker improved. This is why I'm a believer in this therapy.

Last edited: Jun 8, 2026 at 3:58 AM
3 23josh_phd_bmore, roxy_nash, tony_orlando
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Dr.MetabolicMD
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Jun 7, 2026 at 11:58 PM#9
BethLabQueen said:
Comprehensive lipid panel update relevant to the lipid panel: Marker Baseline 6 Months 12 Months Reference Total Cholesterol 232 197 177 <200 LDL…

Omega-3 index improvement on the lipid panel: often overlooked but my omega-3 index went from 4.4% to 8.9% over 13 months. I supplemented with 2g EPA+DHA daily.

This matters because omega-3s are anti-inflammatory and cardioprotective, complementing the GLP-1 benefits. Target omega-3 index is >8%. Combined with the triglyceride reduction from the medication, my lipid profile is the best it's been in decades.

Last edited: Jun 8, 2026 at 1:58 AM
2 22Dr.ObesityMed, HealthEcon_DC
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Dr.AddMedPHL
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Jun 8, 2026 at 4:42 AM#10
BariatricNurseD said:
Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data: Category Marker Before After…

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

I would rather be corrected than agreed with, if it comes to it.

Last edited: Jun 8, 2026 at 6:42 AM
32 7JessicaM_2024, TomFromTexas, mike.trainer_LA and 29 others
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