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ForumsOral GLP-1 AgonistsDanuglipron dose optimization — looking for input Page 3

Danuglipron dose optimization — looking for input

bbq_ray_KC Thu, Jan 9, 2025 at 9:03 AM 12 replies 1,816 viewsPage 3 of 3
marcus_mpls
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Minneapolis, MN
Jan 12, 2025 at 1:52 AM#11
DebRD_ATL said:
Oral semaglutide is absorbed in the stomach with the help of SNAC, which locally raises pH and protects the peptide long enough to cross.

Saving this. It is the first explanation that did not require me to already understand it. Printing the relevant bit and taking it with me.

22 20bbq_ray_KC, oliver_london, tane_welly and 19 others
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jim_asheville
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Asheville, NC
Jan 12, 2025 at 5:46 PM#12

Clinical perspective, offered as context rather than as advice. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

Last edited: Jan 12, 2025 at 8:46 PM
23 21BenResearch_OR, MikeKY_noInsulin, Dr.RaviCardio and 20 others
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InsuranceTom
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Jan 13, 2025 at 9:39 AM#13
VanRx_Mike said:
It is worth asking what the claim would look like if it were false.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

24 22Dr.ReproEndo, lucas_SP_BR, lisa_labSD and 21 others
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TrialTracker_MD
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Jan 14, 2025 at 1:32 AM#14

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

25 23Dr.PulmRoch, maya_sedona, stefan_berlin and 22 others
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mike_mod
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Jan 14, 2025 at 5:25 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. No action needed from anybody.

26 24PurityPaulOR, MaxMetOK, MounjBrad and 23 others
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