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ForumsOral GLP-1 AgonistsHow far away are we really from an oral option — 12 month update Page 5

How far away are we really from an oral option — 12 month update

HPLC_Greg Wed, Jun 4, 2025 at 7:45 PM 47 replies 2,552 viewsPage 5 of 10
DanielChem_CHI
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Jun 6, 2025 at 10:10 PM#21
SleepDoc_PDX said:
One habit that pays for itself: post the method alongside the number.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

Last edited: Jun 7, 2025 at 12:10 AM
3 1fiona_VT, denise_HTX, raj_cambridge
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JennaRN
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Jun 7, 2025 at 10:56 AM#22
SleepDoc_PDX said:
One habit that pays for itself: post the method alongside the number.

This answered a question I did not know how to ask. Sending this to two other people who asked me the same thing last week.

4 2PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 1 other
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rachel_ABQ
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Jun 7, 2025 at 11:41 PM#23

Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Correct me if the detail matters more than I have assumed.

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MaxMetOK
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Jun 8, 2025 at 12:26 PM#24
rachel_ABQ said:
The mechanism and the magnitude are separate questions.

This is my experience too, for whatever a second data point is worth.

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Dr.BariatricHTX
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Jun 9, 2025 at 1:11 AM#25
rachel_ABQ said:
The mechanism and the magnitude are separate questions.

There is a second half to this that has not been said yet. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

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