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ForumsOral GLP-1 AgonistsCost projections for oral non-peptide GLP-1 agonists — anyone have experience? Page 2

Cost projections for oral non-peptide GLP-1 agonists — anyone have experience?

Dr.CardioMD Tue, Feb 24, 2026 at 10:03 AM 23 replies 1,028 viewsPage 2 of 5
LipidDoc_ATL
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Feb 24, 2026 at 10:53 PM#6
DanielChem_CHI said:
Denials are usually procedural rather than clinical, and the order that works reflects that.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Small molecule does not automatically mean cheap. Price is set by what the market will bear and by patent life, not by cost of goods, and I would not assume the savings reach patients.

Worth separating that from cost and coverage, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

16 11rachel_ABQ, traveltech_sara, AttorneyGrant and 13 others
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lucas_SP_BR
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Feb 25, 2026 at 3:56 AM#7

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

15 10Dr.ObesityLA, NurseKim_ATL, paul_denver and 12 others
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Dr.LipidDallas
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Feb 25, 2026 at 8:59 AM#8
LipidDoc_ATL said:
Small molecule does not automatically mean cheap.

Adding the part of the answer the thread has not reached. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Worth separating that from cost and coverage, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Last edited: Feb 25, 2026 at 10:59 AM
14 9cory_ATX, lori_vegas, Dr.PulmRoch and 11 others
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tammy_FL
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Feb 25, 2026 at 2:02 PM#9

One thing that is still open after sarah_TO’s answer:

What actually works on a prior-authorisation denial, as opposed to the list of things that sound like they should work?

13 8Dr.PainCLE, mike_mealprep, NicoleRaleigh and 10 others
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Dr.CardioMD
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Feb 26, 2026 at 2:17 PM#10

OP back with an update, since a thread like this is useless without one.

Update: approved on the third attempt after a peer-to-peer. Nothing about my case changed; only who was doing the talking.

27 2josh_phd_bmore, roxy_nash, tony_orlando and 24 others
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