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Evidence-based GLP-1 & peptide discussion since 2023
ForumsInsurance & AccessCigna now covering Zepbound — looking for input Page 3

Cigna now covering Zepbound — looking for input

Dr.ObesityLA Tue, Dec 2, 2025 at 2:17 AM 12 replies 1,120 viewsPage 3 of 3
BethLabQueen
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Dec 3, 2025 at 2:15 PM#11
EndoResFellow said:
If two explanations both fit, the useful question is which one predicts something the other does not.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

49 22maya_sedona, stefan_berlin, Dr.EM_Chicago and 46 others
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carl_compliance
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Dec 3, 2025 at 4:55 PM#12
stefan_berlin said:
Agreed on the mechanism, with the caveat that the head-to-head used semaglutide 1mg, not 2.4mg.

This is exactly what I could not find anywhere else. Adding it to my notes with a link back to this thread.

50 23BrianDallas92, labquiet_amy, emily_PDX and 47 others
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Dr.NephBHM_UK
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Dec 3, 2025 at 7:35 PM#13
EndoResFellow said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

1 24PharmacoVig_BOS
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LabKate
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Dec 3, 2025 at 10:15 PM#14

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

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mike_mod
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Dec 4, 2025 at 12:55 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.

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