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ForumsPharmacology & MechanismsHas anyone dealt with is there a simple version of how sema vs tirz are different? Page 5

Has anyone dealt with is there a simple version of how sema vs tirz are different?

fiona_glasgow Mon, Jan 20, 2025 at 10:26 AM 26 replies 1,812 viewsPage 5 of 6
Dr.NateNeph
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Jan 26, 2025 at 5:17 AM#21
FDA_TrackerJim said:
One habit that pays for itself: post the method alongside the number.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

Correct me if the detail matters more than I have assumed.

8 6JakeSmashed95, NauseaFreeNow, SteveThurs and 5 others
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mia_MS2
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Jun 2026
Ann Arbor, MI
Jan 27, 2025 at 11:26 AM#22
FDA_TrackerJim said:
One habit that pays for itself: post the method alongside the number.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

9 7FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 6 others
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carlos_SATX
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Oct 2024
San Antonio, TX
Jan 28, 2025 at 5:35 PM#23
FDA_TrackerJim said:
One habit that pays for itself: post the method alongside the number.

Saving this. It is the first explanation that did not require me to already understand it.

10 8Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 7 others
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paige_pharma
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Sep 2024
Omaha, NE
Jan 29, 2025 at 11:45 PM#24

Adding the clinical framing, because it changes how the question reads. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Last edited: Jan 30, 2025 at 12:45 AM
11 9lisa_labSD, adam_van, Dr.SurgeonPGH and 8 others
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adam_van
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Nov 2024
Vancouver, CA
Jan 31, 2025 at 5:56 AM#25
paige_pharma said:
Start from the measurement rather than the conclusion.

Mine went the same way, slower.

12 10hyun_seoul, jim_asheville, matt_MKE and 9 others
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