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ForumsPharmacology & MechanismsHas anyone dealt with molecular dynamics simulations of glp-1r binding? Page 7

Has anyone dealt with molecular dynamics simulations of glp-1r binding?

BrianDallas92 Wed, Apr 16, 2025 at 2:37 AM 36 replies 1,942 viewsPage 7 of 8
JenPlateau
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Sep 17, 2025 at 11:14 PM#31

Clinical perspective, offered as context rather than as advice. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

2 0HPLC_Greg, LibrarianMeg
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AttorneyGrant
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Sep 30, 2025 at 5:55 AM#32
JenPlateau said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Same experience, arrived at from the opposite direction.

Last edited: Sep 30, 2025 at 6:55 AM
3 1laura_annarbor, JenMemphis, pat_auckland
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MASHdoc_SA
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Oct 12, 2025 at 12:29 PM#33
JenPlateau said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Adding the part of the answer the thread has not reached. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Last edited: Oct 12, 2025 at 3:29 PM
4 2JennaRN, LabKate, kate.chem and 1 other
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Dr.AddMedPHL
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Oct 24, 2025 at 6:55 PM#34

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Last edited: Oct 24, 2025 at 8:55 PM
5 3TomFromTexas, mike.trainer_LA, sarah_nash92 and 2 others
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SaraMom3
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Nov 6, 2025 at 1:14 AM#35

One thing that is still open after JenPlateau’s answer:

Was that from a primary source or from a summary of one?

6 4ZaraB_AL, JakeSmashed95, NauseaFreeNow and 3 others
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