Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
OP back with an update, since a thread like this is useless without one.
Reporting back with a partial result, because a partial result is still better than silence. Two of the three things suggested helped; I cannot separate them and I am not going to pretend otherwise.
Dr.AddMedPHL said:The mechanism and the magnitude are separate questions.
Adding the part of the answer the thread has not reached. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.
Ask again with the specifics and you will get a better answer than this one.
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Browse GL BiochemOne concrete data point for the thread. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
A narrower follow-up, since the general answer is now clear:
What did you change at the same time, and can you separate the two now?