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ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears — need advice Page 3

Got off metformin for the first time in 8 years - crying happy tears — need advice

gary_naperville Wed, Sep 10, 2025 at 9:24 PM 29 replies 1,622 viewsPage 3 of 6
wanda_boise
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Sep 14, 2025 at 3:42 PM#11
TinaHashiRN said:
Glycemic variability as the key metric for glycaemic control success: my coefficient of variation (CV) on CGM dropped from 37% to 21%.

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

Last edited: Sep 14, 2025 at 8:42 PM
18 16DanielChem_CHI, marco_milano, pam_columbus and 15 others
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NurseAsh_DET
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Sep 15, 2025 at 9:26 PM#12

Adding the clinical framing, because it changes how the question reads. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

19 17ricardo_MIA, BrianDallas92, labquiet_amy and 16 others
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DataDave
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Sep 17, 2025 at 3:11 AM#13
PedsEndoPhilly said:
PCOS success story with glycaemic control: as someone with polycystic ovary syndrome, this medication has been transformative beyond weight loss.

This is where I part company with the consensus forming above. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

That is the short version; the long version is somebody else's post.

20 18LondonLisa, mike_nyc, VendorMark and 17 others
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anders_CPH
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Sep 18, 2025 at 8:56 AM#14

One concrete data point for the thread. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

Last edited: Sep 18, 2025 at 12:56 PM
21 19BethLabQueen, ChrisMacros, KetoKyle and 18 others
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Admin
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Sep 19, 2025 at 2:42 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Report rather than reply if it drifts again.

22 20PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 19 others
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