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ForumsMetabolic Health & DiabetesGot off metformin for the first time in 8 years - crying happy tears — need advice Page 6

Got off metformin for the first time in 8 years - crying happy tears — need advice

gary_naperville Wed, Sep 10, 2025 at 9:24 PM 29 replies 1,622 viewsPage 6 of 6
PeptideSynthNJ
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Aug 2024
Princeton, NJ
Oct 23, 2025 at 8:09 AM#26

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Ask again with the specifics and you will get a better answer than this one.

Last edited: Oct 23, 2025 at 12:09 PM
4 2wanda_boise, NurseAsh_DET, BenResearch_OR and 1 other
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EndoResFellow
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Sep 2024
Baltimore, MD
Oct 28, 2025 at 2:23 PM#27

A narrower follow-up, since the general answer is now clear:

What did you change at the same time, and can you separate the two now?

5 3TinaHashiRN, robert_kc, dan_philly and 2 others
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tony_orlando
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Nov 2024
Orlando, FL
Nov 2, 2025 at 8:40 PM#28
PeptideSynthNJ said:
If you are going to change something, change one thing and give it long enough to express itself.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

6 4ZaraB_AL, JakeSmashed95, NauseaFreeNow and 3 others
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PharmHunterJen
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Jul 2024
Illinois
Nov 8, 2025 at 3:00 AM#29
PeptideSynthNJ said:
If you are going to change something, change one thing and give it long enough to express itself.

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

7 5Dr.PainCLE, mike_mealprep, NicoleRaleigh and 4 others
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gary_naperville
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Oct 2024
Naperville, IL
Nov 13, 2025 at 9:23 AM#30

Reporting back.

Closing the loop. The answer turned out to depend on the detail I had left out of the opening post, which is a lesson about how to ask rather than about the subject.

29 2RickReta_CO, PharmHunterJen, TomTeleRx and 26 others
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