Oral GLP-1 pipeline overview — all agents in development

One thing that is still open after Dr.NephBHM_UK’s answer:

What would you measure differently if you were starting again?

bri_stats said:

If you are going to change something, change one thing and give it long enough to express itself.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

bri_stats said:

If you are going to change something, change one thing and give it long enough to express itself.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Found this through search years later and it is still the best discussion of the question, so adding one thing. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

From the other side of the consultation, briefly. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.