Has anyone dealt with semaglutide 1.0mg for maintenance?

TrialNerd_Beth said:

Dr.AddMedPHL said: ...but the FDA says semaglutide...

All correct, with the caveat that "maintenance dose" in the literature almost always means the top studied dose. Lower maintenance doses are widely used and thinly evidenced, which is worth knowing before you cite anything as established.

I would rather be corrected than agreed with, if it comes to it.

PharmacoVig_BOS said:

All correct, with the caveat that "maintenance dose" in the literature almost always means the top studied dose.

The regain framing needs pushing back on. Two thirds regained means one third did not, and the trial provided no ongoing support to either group. Treating regain as pharmacologically inevitable is as unsupported as treating maintenance as automatic.

PharmacoVig_BOS said:

All correct, with the caveat that "maintenance dose" in the literature almost always means the top studied dose.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

PharmacoVig_BOS said:

All correct, with the caveat that "maintenance dose" in the literature almost always means the top studied dose.

This answered a question I did not know how to ask. Sending this to two other people who asked me the same thing last week.

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Thread quality here is what the rules are for. Keep it up.