🍪 The GLP Lounge uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsDosing & ProtocolsHas anyone dealt with i missed my shot day by 2 days am i going to be okay? Page 2

Has anyone dealt with i missed my shot day by 2 days am i going to be okay?

JakeSmashed95 Tue, Apr 15, 2025 at 11:49 PM 25 replies 1,966 viewsPage 2 of 5
LabKate
Senior Member
2,678
11,234
Jan 2024
Oregon
Apr 16, 2025 at 12:54 AM#6
JakeSmashed95 said:
A step that is uncomfortable at week two is frequently comfortable at week six with no change in dose, because the gastric-emptying component…

PSA for titration users considering the 0.25mg starting dose: this dose is NOT intended for weight loss. It's a titration dose to let your body adjust. Don't be discouraged if you don't lose much in the first month.

The therapeutic dose for weight management starts at 1.7mg (semaglutide) or 5mg (tirzepatide). Be patient with the ramp-up.

2 22JenMemphis, pat_auckland
Reply Quote Save Share Report
HealthEcon_DC
Member
567
3,456
Apr 2024
Washington, DC
Apr 16, 2025 at 1:19 AM#7

Following on from LindaRN_retired — and this may be the naive question:

Why the interval is four weeks rather than two, and whether a slower ladder gets to the same place?

1 21JessicaH_TX
Reply Quote Save Share Report
Dr.PulmRoch
Member
456
2,345
Jun 2024
Rochester, MN
Apr 16, 2025 at 1:44 AM#8
LabKate said:
PSA for titration users considering the 0.25mg starting dose: this dose is NOT intended for weight loss.

Dose escalation anxiety for titration: I was terrified to move from 0.5mg to 1.0mg based on horror stories in this forum. But my actual experience? Slightly more appetite suppression, zero additional side effects.

Remember that the people posting about terrible side effects are a biased sample. Most people titrate up without drama — they just don't post about it because it's uneventful.

50 20AttorneyGrant, DebRD_ATL, KristenIndy and 47 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
JakeSmashed95
Member
412
1,890
Aug 2024
Arkansas
Online
Apr 16, 2025 at 2:09 AM#9

Closing the loop on my own question.

Closing this out: I held the step for six weeks rather than four and it settled without a dose change. The interval was the answer, not the dose.

49 19Dr.LipidDallas, alex_tucson, kevin_tulsa and 46 others
Reply Quote Save Share Report
Dr.EndoEP
Member
267
1,234
Oct 2024
El Paso, TX
Apr 16, 2025 at 4:11 AM#10
Dr.PulmRoch said:
Dose escalation anxiety for titration: I was terrified to move from 0.5mg to 1.0mg based on horror stories in this forum.

Agreed on the arithmetic, with one condition: holding indefinitely at a dose that is not doing anything is not patience, it is a stall with a nice name. The distinction is whether appetite has changed at all at the current step.

35 8LindaRN_retired, tommy_boulder, hyun_seoul and 32 others
Reply Quote Save Share Report

Similar Threads

Micro-dosing semaglutide — is sub-therapeutic dosing effective?16 replies
Injection technique: subcutaneous depot formation and absorption8 replies
Semaglutide PK modeling — when to time your injection12 replies
Reconstitution calculator — compounded peptide dosing math7 replies
Half-life implications for missed doses — PK-based guidance5 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register