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ForumsPharmacology & MechanismsStructure-function of tirzepatide — my results so far Page 3

Structure-function of tirzepatide — my results so far

TomTeleRx Sun, Mar 1, 2026 at 6:08 AM 12 replies 930 viewsPage 3 of 3
Dr.SportsMedIN
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Mar 4, 2026 at 1:33 PM#11
Dr.RaviCardio said:
It helps to say which part of this you are uncertain about.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

Last edited: Mar 4, 2026 at 6:33 PM
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marco_milano
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Mar 5, 2026 at 5:01 PM#12
SteveThurs said:
Agreed on the mechanism, with the caveat that the head-to-head used semaglutide 1mg, not 2.4mg.

Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.

Last edited: Mar 5, 2026 at 9:01 PM
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BariatricNurseD
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Mar 6, 2026 at 8:30 PM#13
Dr.RaviCardio said:
It helps to say which part of this you are uncertain about.

This is where I part company with the consensus forming above. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.

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Dr.GutHealth
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Mar 7, 2026 at 11:59 PM#14

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

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mike_mod
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Mar 9, 2026 at 3:29 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Tagging this one for the weekly digest.

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