Structure-function of tirzepatide — my results so far

anders_CPH said:

The GIP arm is doing real work rather than padding the label.

Pushing back on anders_CPH here. The "tirzepatide is simply better" summary irritates me. It is better on mean weight loss, and the cardiovascular outcome evidence is far thinner than semaglutide's. If the reason for treating is cardiovascular risk rather than weight, the evidence base points the other way.

The figures, for anyone assembling their own picture. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

JessicaH_TX said:

The "tirzepatide is simply better" summary irritates me.

There is a second half to this that has not been said yet. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

Following on from SteveThurs — and this may be the naive question:

Whether anyone has held 10mg long term rather than climbing, and what happened over the following year?

Reporting back.

Update: the eight-week restart pattern people described is exactly what happened. I nearly abandoned it at week five.