Dr.CardioMD said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
Correct me if the detail matters more than I have assumed.
EndoResFellow said:The mechanism is more central than most summaries suggest.
Genuinely useful, thank you. I had the facts and not the framework. Taking it to my next appointment.
Dr.CardioMD said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.
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View ResultsAdding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.