Steady-state concentrations across dose tiers — anyone have experience?

Dr.PulmRoch said:

Practical: whatever you change, write down the date and the reason.

Genuinely useful, thank you. I had the facts and not the framework.

Reporting back.

My error was treating units as a mass. Once I wrote mg/ml on the vial in marker and worked in millilitres first, the two of us got the same answer.

Dr.ReproEndo said:

Once I wrote mg/ml on the vial in marker and worked in millilitres first, the two of us got the same answer.

Can confirm. Same sequence, different timescale.

Dr.ReproEndo said:

Once I wrote mg/ml on the vial in marker and worked in millilitres first, the two of us got the same answer.

There is a second half to this that has not been said yet. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.